Lori shows up in the official sketch of Brian Heder: his third wife, beside him while the boatyard is still running. Rockstar has not given a last name or a storyline of her own.
Brian's profile says the two still move product through the boatyard together, and that Jason is expected to stop by for Lori's sangria now and then. That is everything Rockstar has said about her so far.
Guides that study the trailer footage say she is shown handling an assault rifle and a pistol, which suggests she is more than a bystander in the business. Rockstar has not confirmed her role in the story or a voice actor.